Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity
Monday, March 27th, 2023
Siyao Li, Man J Livingston, Zhengwei Ma, Xiaoru Hu, Lu Wen, Han-Fei Ding, Daohong Zhou, Zheng Dong, “Tubular cell senescence promotes maladaptive kidney repair and
Na/K-ATPase signaling tonically inhibits sodium reabsorption in the renal proximal tubule
Monday, March 6th, 2023
Shreya T. Mukherji, Luca Brambilla, Kailey B. Stuart, Isabella Mayes, Laura C. Kutz, Yiliang Chen, Leandro A. Barbosa, Ibrahim Elmadbouh, Jeff P. McDermott, Steven T.
Subtotal Nephrectomy Associated with a High-Phosphate Diet in Rats Mimics the Development of Calcified Aortic Valve Disease Associated with Chronic Renal Failure
Tuesday, February 21st, 2023
Hind Messaoudi,Thomas Levesque, Nicolas Perzo, Elodie Berg, Guillaume Feugray, Anaïs Dumesnil, Valéry Brunel, Dominique Guerrot, Hélène Eltchaninoff, Vincent Richard, Saïd Kamel, Eric Durand, Youssef Bennis,
The effects of excess salt intake on the kidney metabolism in Sprague-Dawley rats
Thursday, January 26th, 2023
Satoshi Shimada, Brian R. Hoffmann, Chun Yang, Theresa Kurth, Andrew S. Greene, Mingyu Liang, Ranjan K. Dash, Allen W. Cowley Jr, “The effects of excess
Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery
Wednesday, January 25th, 2023
Zhao, Zhi Bo, Marschner, Julian A., Iwakura, Takamasa, Li, Chenyu, Motrapu, Manga, Kuang, Meisi, Popper, Bastian, Linkermann, Andreas, Klocke, Jan, Enghard, Philipp, Muto, Yoshiharu, Humphreys,
Fibroblast Growth Factor 2 Is Produced By Renal Tubular Cells to Act as a Paracrine Factor in Maladaptive Kidney Repair After Cisplatin Nephrotoxicity
Monday, January 16th, 2023
Xiaoru Hu, Zhengwei Ma, Siyao Li, Lu Wen, Yuqing Huo, Guangyu Wu, Santhakumar, Manicassamy, Zheng Dong, “Fibroblast Growth Factor 2 Is Produced By Renal Tubular
Intrarenal Dopaminergic System Is Dysregulated in SS-Resp18mutant Rats
Wednesday, January 4th, 2023
Usman M. Ashraf, Ealla Atari, Fawaz Alasmari, Harshal Waghulde, Vikash Kumar, Youssef Sari, Sonia M. Najjar, Pedro A. Jose and Sivarajan Kumarasamy, *”Intrarenal Dopaminergic System
Protective effect of Cistanche deserticola on gentamicin-induced nephrotoxicity in rats
Tuesday, December 20th, 2022
Rui-bin Bai, Jing-min Fan, Yan-ping Wang, Yan Wang, Xue Li, Fang-di Hu, “Protective effect of Cistanche deserticola on gentamicin-induced nephrotoxicity in rats”, Chinese Herbal Medicine,
Obesity-Related Kidney Disease
Wednesday, November 9th, 2022
Manoj K. Datta, Trupti Joshi, Sidharth Sen, Pallav Singh, Ricardo J. Restrepo, Jing Ren, Ravi Nistala. ASN Kidney Week Abstract Supplement 2022: SA-PO968
Detrimental Role of Hypoxia-Inducible Factor Asparaginyl Hydroxylase (FIH) in CKD
Wednesday, November 9th, 2022
Anna Faivre, Romain Dissard, Willy Kuo, Thomas Verissimo, David Legouis, Gregoire Arnoux, Maja Lindenmeyer, Solange Moll, Carsten C. Scholz, Vartan Kurtcuoglu, Sophie M. De Seigneux.
Blockade Ameliorates Cardiorenal Syndrome in the db/db Type 2 Diabetes Mouse Model
Wednesday, November 9th, 2022
Ander Vergara, Conxita Jacobs Cachá, Carmen Llorens Cebrià, Pamela Domínguez Báez, Nerea Martos, Irene Martínez Díaz, Sheila Bermejo, Michael P. Pieper, Begoña Benito, Maria Jose
Diabetes and Obesity Increase the Severity of Ischemia-Reperfusion Induced AKI in ZSF1 Rats
Wednesday, November 9th, 2022
Li-Jun Ma, Fuyong Du, 1KamalAlbarazanji, Jianying Liu, Qiu Li, 1Lili Guo, Jenson Qi, George Ho, Rong Meng, Tao Chen, Raul Camacho, Andrea R. Nawrocki. ASN
Prerenal Azotemia Triggers the Hepatic Acute Response in a Novel, Clinically Defined Murine Model
Tuesday, November 8th, 2022
Kayo Okamura, Sizhao Lu, Zhibin He, John R. Montford, Mary C. Weiser-Evans, Sarah Faubel, “Prerenal Azotemia Triggers the Hepatic Acute Response in a Novel, Clinically
Tubular cell polyploidy protects from lethal acute kidney injury but promotes consequent chronic kidney disease
Thursday, October 6th, 2022
Letizia De Chiara, Carolina Conte, Roberto Semeraro, Paula Diaz-Bulnes, Maria Lucia Angelotti, Benedetta Mazzinghi, Alice Molli, Giulia Antonelli, Samuela Landini, Maria Elena Melica, Anna Julie
Gasdermin D-deficient mice are hypersensitive to acute kidney injury
Thursday, September 22nd, 2022
Wulf Tonnus, Francesca Maremonti, Alexia Belavgeni, Markus Latk, Yoshihiro Kusunoki, Anne Brucker, Anne von Mässenhausen, Claudia Meyer, Sophie Locke, Florian Gembardt, Kristina Beer, Paul Hoppenz,
Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy
Tuesday, July 5th, 2022
Karen I. L opez-Cayuqueo, Rosa Planells-Cases, Matthias Pietzke, Anna Oliveras, Stefan Kempa, Sebastian Bachmann, and Thomas J. Jentsch, “Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy,”
The Release of 24 h Infravesical Obstruction in Mice: Changes in Molecular, Morphological, and Functional Parameters for 14-Day Observation
Tuesday, May 31st, 2022
Yutao Lu, Scott R. Manson, Isabela Bastos Binotti Abreu de Araujo, Paul F. Austin, Jens C. Djurhuus, L. Henning Olsen and Rikke Nørregaard, “The Release
Paraoxonase-1 Regulation of Renal Inflammation and Fibrosis in Chronic Kidney Disease
Monday, May 9th, 2022
Fatimah K. Khalaf, Chrysan J. Mohammed, Prabhatchandra Dube, Jacob A. Connolly, Apurva Lad, Usman M. Ashraf, Joshua D. Breidenbach, Robin C. Su, Andrew L. Kleinhenz,
Inhibition of Na-H exchanger 3 ameliorates lower limb ischemia/reperfusion-induced acute kidney injury through preservation of mitochondrial biogenesis in mice
Monday, April 11th, 2022
Balamurugan Packialakshmi, Ian Stewart, David Burmeister, Xiaoming Zhou, Kevin Chung, Xiao Li, Manoocher Soleimani, Jia Zhuo, Lee Ann MacMillan-Crow, “Inhibition of Na-H exchanger 3 ameliorates
Myristoylated Protein Kinase C Beta II Inhibitor Attenuates Renal Injury in Mice Subjected to Severe Bilateral Ischemia-Reperfusion
Monday, April 11th, 2022
Lisa Shah, Devani Johnson, Alexis Verwoert, Sunit Singh, Tameka Dean, Qian Chen, Robert Barsotti, Yanlin Jiang, James George, Anupam Agarwal, Lindon Young, “Myristoylated Protein Kinase
Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
Tuesday, March 29th, 2022
Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou, Christelle Veyrat-Durebex, Carolyn Heckenmeyer, Marylise Fernandez, Lena Berchtold, Delal Dalga, Clemens Cohen, Maarten Naesens, Sven-Erik
Validation of HDAC8 Inhibitors as Drug Discovery Starting Points to Treat Acute Kidney Injury
Tuesday, March 29th, 2022
Keith Long, Zoe Vaughn, Michael David McDaniels, Sipak Joyasawal, Aneta Przepiorski, Emily Parasky, Veronika Sander, David Close, Paul A.Johnston, Alan J. Davidson, Mark de Caestecker,
Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive monitoring methods
Tuesday, March 29th, 2022
Rachel Harwood, Joshua Bridge, Lorenzo Ressel, Lauren Scarfe, Jack Sharkey, Gabriela Czanner, Philip A Kalra, Aghogho Odudu, Simon Kenny, Bettina Wilm, Patricia Murray, “Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive
Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury
Friday, March 11th, 2022
Andrea Sánchez-Navarro, Miguel Ángel Martínez-Rojas, Adrián Albarrán-Godinez, Rosalba Pérez-Villalva, Johan Auwerx, Abigail de la Cruz, Lilia G. Noriega, Florencia Rosetti, and Norma A. Bobadilla, “Sirtuin
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Friday, March 11th, 2022
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
p53 in Proximal Tubules Mediates Chronic Kidney Problems after Cisplatin Treatment
Thursday, February 24th, 2022
Shuangshuang Fu, Xiaoru Hu, Zhengwei Ma, Qingqing Wei, Xiaohong Xiang, Siyao Li, Lu Wen, Yumei Liang and Zheng Dong, “p53 in Proximal Tubules Mediates Chronic
Effects of Combination of RTA nh404 and Dapagliflozin on Renal Involvement and Body Composition in Experimental Rat Model of Diabetic Kidney Disease
Thursday, February 24th, 2022
Fukami, K, Ota, K, Kodama, G, Yokota, Y, Shinohara, M, Ito, S, “Effects of Combination of RTA nh404 and Dapagliflozin on Renal Involvement and Body
Mechanism of the Canagliflozin-Induced Early Decline in GFR in Obese Diabetic Rats
Thursday, February 24th, 2022
Kodama, G, Kaida, Y, Ito, S, Ohta, K, Yokota, Y, Shinohara, M, Fukami, K, “Mechanism of the Canagliflozin-Induced Early Decline in GFR in Obese Diabetic
Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages
Wednesday, February 16th, 2022
Viviane Gnemmi, Qiubo Li, Qiuyue Ma, Letizia De Chiara, Giulia Carangelo, Chenyu Li, Mireia Molina-Van den Bosch, Paola Romagnani, Hans-Joachim Anders and Stefanie Steiger,”Asymptomatic Hyperuricemia
Salt loading with unilateral nephrectomy accelerates decline in glomerular filtration rate in the hypertensive, obese, type 2 diabetic SDT fatty rat model of diabetic kidney disease
Thursday, February 3rd, 2022
Yuichi Shinozaki, Yuko Katayama, Fuminari Yamaguchi, Tomohisa Suzuki, Kana Watanabe, Kinuko Uno, Takahiro Tsutsui, Miki Sugimoto, Masami Shinohara, Katsuhiro Miyajima, Takeshi Ohta, “Salt loading with
Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery system for enhanced bioactivity with reduced renal injury induced by NSAIDs
Tuesday, January 25th, 2022
Wenhao Xu, Jinli Yang, Xiangyang Gu, Wenjing Su, Faxiang Pu, Zhangfu Xie, Kongliang Jin, Weike Su & Lichan Mao,”Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery
Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure
Tuesday, December 28th, 2021
Andrea K. Brown, Alyssa Nichols, Chantell A. Coley, Ubong S. Ekperikpe, Kasi C. McPherson, Corbin A. Shields, Bibek Poudel, Denise C. Cornelius, Jan M. Williams,
Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
Tuesday, December 28th, 2021
Philipp Tauber, Frederick Sinha, Raffaela S. Berger, Wolfram Gronwald, Katja Dettmer, Michaela Kuhn, Maximilian Trum, Lars S. Maier, Stefan Wagner, Frank Schwed, “Empagliflozin Reduces Renal
Dichotomous responses to chronic fetal hypoxia lead to a predetermined aging phenotype
Tuesday, December 28th, 2021
Stefan Rudloff, Andrea Bileck, Lukas Janker, Nicola Wanner, Nastassia Liaukouskaya, Carsten Lundby, Tobias B. Huber, Christopher Gerner, Uyen Huynh-Do, “Dichotomous responses to chronic fetal hypoxia
Activation of the Hypoxia-Inducible Factor Pathway Inhibits Epithelial Sodium Channel–Mediated Sodium Transport in Collecting Duct Principal Cells
Wednesday, December 8th, 2021
Eva Dizin, Valérie Olivier, Isabelle Roth, Ali Sassi, Grégoire Arnoux, Suresh Ramakrishnan, Sandrine Morel, Brenda R. Kwak, Johannes Loffing, Edith Hummler, Roland H. Wenger, Ian
A new view of macula densa cell protein synthesis
Wednesday, December 8th, 2021
Urvi Nikhil Shroff, Georgina Gyarmati, Audrey Izuhara, Sachin Deepak, and János Peti-Peterdi, “A new view of macula densa cell protein synthesis”, American Journal of Physiology,
Kidney vascular congestion exacerbates acute kidney injury in mice.
Wednesday, December 8th, 2021
Takashi Kitani, Kengo Kidokoro, Tomohiro Nakata, Yuhei Kirita, Itaru Nakamura, Kunihiro Nakai, Aya Yagi-Tomita, Tomoharu Ida, Noriko Uehara-Watanabe, Kisho Ikeda, Noriyuki Yamashita, Benjamin D. Humphreys,
Novel Keap1-Nrf2 Protein-protein interaction inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome mouse model
Wednesday, December 8th, 2021
Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou,
Relaxin attenuates organ fibrosis via an angiotensin-type 2 receptor mechanism in aged hypertensive female rats
Tuesday, November 30th, 2021
Giannie Barsha, Sarah Walton, Edmund Kwok, Katrina Mirabito Colafella, Anita Pinar, Lucinda Hilliard Krause, Tracey Gaspari, Robert Widdop, Chrishan Samuel and Kate Denton, “Relaxin attenuates
Expanded renal lymphatics improve recovery following kidney injury
Tuesday, November 30th, 2021
Gaurav Baranwal, Heidi A. Creed, Laurence M. Black, Alexa Auger, Alexander M. Quach, Rahul Vegiraju, Han E. Eckenrode, Anupam Agarwal, Joseph M. Rutkowski, “Expanded renal
Crescents Derive from Single Podocyte Progenitors and a Drug Enhancing Their Differentiation Attenuates Rapidly Progressive Glomerulonephritis
Wednesday, November 17th, 2021
Maria Elena Melica, Giulia Antonelli, Maria Lucia Angelotti, Gianmarco Lugli, Carolina Conte, Letizia De Chiara, Fiammetta Ravaglia, Anna J. Peired, Benedetta Mazzinghi, Elena Lazzeri, Roberto
Paraoxonase-3 Regulation of Cardiotonic Steroids Mediates Renal Injury and Dysfunction in a Dahl Salt Sensitive Model of Chronic Kidney Disease
Tuesday, November 16th, 2021
Chrysan J Mohammed, Sabitri Lamichhane, Prabhatchandra Dube, Sophia Soehnlen, Jacob Connolly, Andrew Kleinhenz, Dhilhani Faleel, Dragan Isailovic, Deepak Malhotra, Steven Haller, David J Kennedy, “Paraoxonase-3
Probiotics Supplementation Protects the Transition from AKI to CKD in Aged Mice via the Kidney-Gut Axis
Tuesday, November 16th, 2021
Myung-Gyu Kim, Yina Fang, Ko Yoon Sook, Lee Hee Young, Jihyun Yang, Sewon Oh, Sang-Kyung Jo, Won-Yong Cho, “Probiotics Supplementation Protects the Transition from AKI
The Brain-Gut-Kidney Axis in the Development of Cognitive Dysfunction Following AKI
Tuesday, November 16th, 2021
Young Eun Choi, Jihyun Yang, Ko Yoon Sook, Lee Hee Young, Yina Fang, Sewon Oh, Myung-Gyu Kim, Won-Yong Cho, Sang-Kyung Jo, “The Brain-Gut-Kidney Axis in
Role of Collagen Receptors in Radiation-Induced Nephrotoxicity
Tuesday, November 16th, 2021
Anis Ahmad, Jumana Afaghani, Junwei Shi, Saba Ansari, Jin Ju Kim, Yan Shi, Sandra M. Merscher, Alan Pollack, Youssef Zeidan, Alessia Fornoni, Brian Marples, “Role
Time-Restricted Feeding Ameliorates Fibrosis by Restoring Disrupted Peripheral Clock in Adenine-Induced CKD Model
Tuesday, November 16th, 2021
Yina Fang, Sewon Oh, Jihyun Yang, Ko Yoon Sook, Hee Young Lee, Sang-Kyung Jo, Won-Yong Cho, Myung-Gyu Kim, “Time-Restricted Feeding Ameliorates Fibrosis by Restoring Disrupted
Novel Keap-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates the Severity of Experimental Alport Syndrome
Tuesday, November 16th, 2021
Shota Kaseda, Mary Ann Suico, Sayaka Ogi, Hidetoshi Sunamoto,Hirohiko Fukiya, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai, “Novel Keap-Nrf2 Protein-Protein Interaction Inhibitor UBE-1099 Ameliorates
Pharmacological Validation of HDAC8 as a Therapeutic Target for AKI
Tuesday, November 16th, 2021
Donna M. Huryn, Keith E. Long, Michael D. McDaniels, Rachel Delgado, Zoe Vaughn,Prema C. Iyer, Veronika Sander, Alan J. Davidson, Mark P. de Caestecker, Neil
UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation
Tuesday, November 16th, 2021
Sayaka Ogi, Hidetoshi Sunamoto, Hirohiko Fukiya, Futoshi Nara, Kazuhiro Onuma, “UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation”, Am.
The Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Left Ventricular Function in Preclinical Diabetic CKD
Tuesday, November 16th, 2021
Ixchel Q. Lima Posada, Yohan Stephan, Matthieu Soulié, Benjamin Bonnard, Roberto Palacios Ramirez, Lionel Nicol, Peter Kolkhof, Paul Mulder, Frederic Jaisser, “The Nonsteroidal Mineralocorticoid Receptor
