Gain access to exclusive preclinical content.
Complete the form below. We'll assign a user name and password, then send you a link. Thanks!

Get Access Register

EXCLUSIVE PRECLINICAL CONTENT.
You must log in to access content on this page. Or click here to request access.
Role of Anaphylatoxin Receptors C5aR1 and C5aR2 in Hypertension and Hypertensive End-Organ Damage
Monday, November 11th, 2024
Leonie Dreher, Sarah Walachowski, Georg R. Herrnstadt, Nicolas Ehnert, Catherine Meyer-Schwesinger, Joerg Koehl, Tobias B. Huber, Markus Bosmann, Ulrich O.Wenzel. ASN Abstract supplement J Am
Abstract P178: Sex Differences in the Role of the Immune ET-1/ETA Axis in Controlling Blood Pressure during a Hypertension Challenge
Thursday, November 7th, 2024
Abigail Brooks, Sara Biswal, and Carmen De Miguel, “Abstract P178: Sex Differences in the Role of the Immune ET-1/ETA Axis in Controlling Blood Pressure during
Abstract 03: Glomerular Hyperfiltration Promotes Chronic Kidney Disease through Interleukin 17A-Mediated Inflammation
Thursday, November 7th, 2024
Jing Liu, Luojing Chen, Thu Le, and Jing Wu, “Abstract 03: Glomerular Hyperfiltration Promotes Chronic Kidney Disease through Interleukin 17A-Mediated Inflammation”, AHAIASA Journals, Hypertension, Volume
Abstract P145: The Biological Effects of Cross-Sex Hormone Therapy in the Male Rat Does Not Enhance Renal Risk in Young Adulthood
Thursday, November 7th, 2024
Jordan Mallette, Breland Crudup, Alex Willis, Kathy Cockrell, Licy Yanes Cardozo, and Barbara Alexander, “Abstract P145: The Biological Effects of Cross-Sex Hormone Therapy in the
Effects of empagliflozin on cardio-renal interaction in heart failure with reduced ejection fraction: results from in-vivo experiments and the CINNAMON-study
Monday, November 4th, 2024
F Sinha, S Klatt, A Rietmann, A Schoepperl, L Maier, F Schweda, S Wagner, “Effects of empagliflozin on cardio-renal interaction in heart failure with reduced
Impact of inhibition of the renin-angiotensin system on early cardiac and renal abnormalities in Sprague Dawley rats fed short-term high fructose plus high salt diet
Monday, August 26th, 2024
Sharif Hasan Siddiqui, Rebekah Pitpita, Boycho Boychev, Dragana Komnenov and Noreen F. Rossi, “Impact of inhibition of the renin-angiotensin system on early cardiac and renal
Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male Sprague-Dawley rats
Friday, July 26th, 2024
Debra L. Irsik, Jian-Kang Chen, Wendy B. Bollag, and Carlos M. Isales, “Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male
Toll-like receptor 4 mutation mitigates gut microbiota-mediated hypertensive kidney injury
Monday, July 15th, 2024
Suravi Majumder, Sathnur B. Pushpakumar, Hebah Almarshood, Rosemary Ouseph, Dibson D. Gondim, Venkatakrishna R. Jala, Utpal Sen, “Toll-like receptor 4 mutation mitigates gut microbiota-mediated hypertensive
Integrated renal and sympathetic mechanisms underlying the development of sex- and age-dependent hypertension and the salt sensitivity of blood pressure
Wednesday, July 10th, 2024
Alissa A. Frame, Kayla M. Nist, Kiyoung Kim, Franco Puleo, Jesse D. Moreira, Hailey Swaldi, James McKenna 3rd, Richard D. Wainford, “Integrated renal and sympathetic
Role of the anaphylatoxin receptor C5aR2 in angiotensin II induced hypertension and hypertensive end organ damage
Friday, July 5th, 2024
Leonie Dreher, Marlies Bode, Nicolas Ehnert, Catherine Meyer-Schwesinger, Thorsten Wiech, Jörg Köhl, Tobias B Huber, Tilo Freiwald, Georg R Herrnstadt, Ulrich O Wenzel, “Role of
Global Deletion of DPP4 Prevents the Development of Salt-sensitive Hypertension in Obese Mice via Regulation of Sodium and Water Excretion
Thursday, May 30th, 2024
Flavia Martins, Rohit Allada, Jing Ren, Ricardo Restrepo, Adriana Girardi, and Ravi Nistala. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1647
Impact of Renin Angiotensin System Inhibition on Renal Function in Fructose-induced Salt Sensitive Blood Pressure
Thursday, May 30th, 2024
Rebekah Pitpitan, Sharif Siddiqui, Boycho Boychev, and Noreen Rossi. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1241
The Role of Interleukin-6 in Regulating Glomerular Filtration Rate during Angiotensin II and High Salt Conditions
Thursday, May 30th, 2024
Mark Hatcher, Rong Duan, and Dexter Lee. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1923
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Friday, February 9th, 2024
Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois
A heart derived-soluble factor which controls kidney and cardiovascular function after acute cardiorenal syndrome
Monday, January 29th, 2024
Michael Hutchens, Yoshio Funahashi, Jessica Hebert, Adam Munhall, Kevin Burfeind, Elizabeth Nguyen, Tahnee Groat, Megan Nickerson1, Mahaba Eiwaz, Nicole Andeen, Motoko Yanagita, Susan Gurley, “A
Combining renin-angiotensin system blockade and sodium-glucose cotransporter-2 inhibition in experimental diabetes results in synergistic beneficial effects
Friday, December 15th, 2023
Edwyn O Cruz-López, Dien Ye, Daniel G Stolk, Marian C Clahsen-van Groningen, Richard van Veghel, Ingrid M Garrelds, Marko Poglitsch, Oliver Domenig, Rahi S Alipour
Preventing Kidney Failure in Hemolytic Anemias with a Novel Heme and Hemoglobin Scavenger
Monday, December 4th, 2023
Daniela Lucas PhD, Pedro Cabrales PhD, Carlos J Munoz MS,BS, Srila Gopal MD, Cynthia R Muller PhD, “Preventing Kidney Failure in Hemolytic Anemias with a
Low Cl- Diet Protects from Hypertension and Cardiac Hypertrophy After AngII Infusion in Mice Preserving Natriuresis
Friday, November 10th, 2023
Luis F. Michea, Jessica C. Liberona, Pablo A. Leon. ASN Abstract supplement J Am Soc Nephrol 34: 2023 FR- PO357.
Diabetic Kidney Disease (DKD)-Induced Cardiac Damage Is Characterized and Reduced by Standard-of-Care Treatment in a Translational Diet-Induced Hypertension-Accelerated Mouse Model of DKD
Friday, November 10th, 2023
Arianne Van Koppen, Andrea R. Nawrocki, Simon A. Hinke, Harry van Goor, Amélie Dendooven, Tri Q. Nguyen, Matthew D. Breyer. ASN Abstract supplement J Am
Heart-Specific LIM Protein (CSRP3) as a Novel Cardiorenal Connector in Acute Cardiorenal Syndrome-Related CKD Progression
Friday, November 10th, 2023
Yoshio Funahashi, Michael Hutchens. ASN Abstract supplement J Am Soc Nephrol 34: 2023 TH-OR01.
Adipocyte (Pro)Renin Receptor Via SPRR Regulates Renal Sodium-glucose Cotransporter-2 Expression And Glomerular Filtration Rate In Mice
Wednesday, October 18th, 2023
Huaqing Zheng, Changjiang zou, Kannaree Kaewsaro, Fei Wang, Ziwei Fu and Tianxin Yang, “Adipocyte (Pro)Renin Receptor Via SPRR Regulates Renal Sodium-glucose Cotransporter-2 Expression And Glomerular
Evidence Of Increased Glycolysis In Renal Cortex Of High Salt Fed Sprague Dawley Rats
Wednesday, October 18th, 2023
Satoshi Shimada, Brian Hoffmann, Chun Yang, Theresa Kurth, Andrew Greene, Mingyu Liang, Ranjan K Dash and Allen W Cowley, “Evidence Of Increased Glycolysis In Renal
Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application
Monday, July 24th, 2023
Robert Moritz, Lee Mangum, Chet Voelker, Gerardo Garcia, Joseph Wenke, “Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application”, BMJ, 16 June 2023,
Pulmonary hypertension without heart failure causes cardiorenal syndrome in a porcine model
Sunday, June 11th, 2023
Arthur Orieux, Chloé Samson, Laurence Pieroni, Sarah Drouin, Simon Dang Van, Tiffany Migeon, Perrine Frere, Dorothée Brunet, David Buob, Juliette Hadchouel, Julien Guihaire, Olaf Mercier
Knockdown of histone deacetylase 1 in fibroblasts and pericytes prevents renal interstitial fibrosis after ischemia-reperfusion injury
Tuesday, May 30th, 2023
Huy Nguyen, Luciano Mendoza, Ariana Ramos, Kelly Hyndman, “Knockdown of histone deacetylase 1 in fibroblasts and pericytes prevents renal interstitial fibrosis after ischemia-reperfusion injury”, American
Sequential afferent and sympathetic renal denervation impact on cardiovascular and renal homeostasis in the male Sprague-Dawley rat
Thursday, May 11th, 2023
Irin Parvin, Madeline M. Gauthier, Melissa R. Dennis, Noah M. Encinas, Ellen L. Nangia, Kyle L. Schwartz, Christopher T. Banek, “Sequential afferent and sympathetic renal
Genetic Deletion of AT1a Receptor or Na+/H+ Exchanger 3 Selectively in the Proximal Tubules of the Kidney Attenuates Two-Kidney, One-Clip Goldblatt Hypertension in Mice
Tuesday, May 9th, 2023
Xiao Chun Li, Rumana Hassan, Ana Paula O. Leite, Akemi Katsurada, Courtney Dugas, Ryosuke Sato and Jia Long Zhuo, “Genetic Deletion of AT1a Receptor or
A myogenic program is enacted by cardiac protein CSRP3 in human and mouse kidney APS Summit 2023: Part of Advances in Renal Physiology II
Tuesday, May 9th, 2023
Yoshio Funahashi, Jonathan Nelson, Kevin Burfeind, Adam Munhall, Tahnee Groat, Michael Hutchens
Peripheral chemoreflex modulation of renal hemodynamics and renal tissue PO2 in chronic heart failure with reduced ejection fraction
Monday, May 8th, 2023
Kiefer W. Kious, Andrew Philipose, Luke J. Smith, Jayson P. Kemble, Stephanie C. E. Twohey, Kalie Savage, Hugo. Díaz, Rodrigo Del Rio, and Noah J.
Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice
Friday, April 14th, 2023
Yi Wang, Linnan Bai, Jiejun Wen, Fangfei Zhang, Sijie Gu, Feng Wang, Jianyong Yin, and Niansong Wang, “Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling
Subtotal Nephrectomy Associated with a High-Phosphate Diet in Rats Mimics the Development of Calcified Aortic Valve Disease Associated with Chronic Renal Failure
Tuesday, March 14th, 2023
Hind Messaoudi, Thomas Levesque, Nicolas Perzo, Elodie Berg, Guillaume Feugray, Anaïs Dumesnil, Valéry Brunel, Dominique Guerrot, Hélène Eltchaninoff, Vincent Richard, Saïd Kamel, Eric Durand, Youssef
Intrarenal Dopaminergic System Is Dysregulated in SS-Resp18mutant Rats
Monday, February 27th, 2023
Usman M. Ashraf, Ealla Atari, Fawaz Alasmari, Harshal Waghulde, Vikash Kumar, Youssef Sari, Sonia M. Najjar, Pedro A. Jose, and Sivarajan Kumarasamy, “Intrarenal Dopaminergic System
Deficiency of complement C3a and C5a receptors does not prevent angiotensin II– induced hypertension and hypertensive end-organ damage
Monday, January 30th, 2023
Marlies Bode, Georg Rudolf Herrnstadt, Leonie Dreher, Nicolas Ehnert, Pia Kirkerup, Maja T. Lindenmeyer, Catherine Meyer- Schwesinger, Heimo Ehmke, Jörg Köhl, Tobias B. Huber, Thorsten
Intrarenal Dopaminergic System Is Dysregulated in SS-Resp18mutant Rats
Wednesday, January 4th, 2023
Usman M. Ashraf, Ealla Atari, Fawaz Alasmari, Harshal Waghulde, Vikash Kumar, Youssef Sari, Sonia M. Najjar, Pedro A. Jose and Sivarajan Kumarasamy, *”Intrarenal Dopaminergic System
Renal TLR-7/ TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension
Friday, November 18th, 2022
Sarika Chaudhari, Bradley M. D’Souza, Jessica Y. Morales, Cassandra M. Young-Stubbs, Caroline G. Shimoura, Rong Ma, and Keisa W. Mathis, “Renal TLR-7/ TNF-α pathway as
Blockade Ameliorates Cardiorenal Syndrome in the db/db Type 2 Diabetes Mouse Model
Wednesday, November 9th, 2022
Ander Vergara, Conxita Jacobs Cachá, Carmen Llorens Cebrià, Pamela Domínguez Báez, Nerea Martos, Irene Martínez Díaz, Sheila Bermejo, Michael P. Pieper, Begoña Benito, Maria Jose
Diabetes and Obesity Increase the Severity of Ischemia-Reperfusion Induced AKI in ZSF1 Rats
Wednesday, November 9th, 2022
Li-Jun Ma, Fuyong Du, 1KamalAlbarazanji, Jianying Liu, Qiu Li, 1Lili Guo, Jenson Qi, George Ho, Rong Meng, Tao Chen, Raul Camacho, Andrea R. Nawrocki. ASN
Mechanisms of Difference in AKI-CKD Transition due to Acute Cardiorenal Syndrome and Ischemia-Reperfusion Injury
Wednesday, November 9th, 2022
Yoshio Funahashi, Jessica F. Hebert, Adam C. Munhall, Megan N. Nickerson, Michael Hutchens. ASN Kidney Week Abstract Supplement 2022: TH-PO086
A Novel Animal Model to Study Delayed Resuscitation Following Traumatic Hemorrhage
Tuesday, August 30th, 2022
Lusha Xiang, Alfredo S. Calderon, Harold G. Klemcke, Carmen Hinojosa-Laborde, Sandra C. Becerra, and Kathy L. Ryan, “A Novel Animal Model to Study Delayed Resuscitation
Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet
Thursday, April 28th, 2022
Chetan N. Patil, McKenzie L. Ritter, Kelsey K. Wackman, Vanessa Oliveira, Kirthikaa Balapattabi, Connie C. Grobe, Daniel T. Brozoski, John J. Reho, Pablo Nakagawa, Gary
Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension
Tuesday, April 12th, 2022
Jing Wu, Shi Fang, Ko-Ting Lu, Gaurav Kumar, John J Reho, Daniel T Brozoski, Adokole J Otanwa, Chunyan Hu, Kelsey K Wackman, Larry N Agbor,
Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive monitoring methods
Tuesday, March 29th, 2022
Rachel Harwood, Joshua Bridge, Lorenzo Ressel, Lauren Scarfe, Jack Sharkey, Gabriela Czanner, Philip A Kalra, Aghogho Odudu, Simon Kenny, Bettina Wilm, Patricia Murray, “Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Friday, March 11th, 2022
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure
Tuesday, December 28th, 2021
Andrea K. Brown, Alyssa Nichols, Chantell A. Coley, Ubong S. Ekperikpe, Kasi C. McPherson, Corbin A. Shields, Bibek Poudel, Denise C. Cornelius, Jan M. Williams,
Kidney vascular congestion exacerbates acute kidney injury in mice.
Wednesday, December 8th, 2021
Takashi Kitani, Kengo Kidokoro, Tomohiro Nakata, Yuhei Kirita, Itaru Nakamura, Kunihiro Nakai, Aya Yagi-Tomita, Tomoharu Ida, Noriko Uehara-Watanabe, Kisho Ikeda, Noriyuki Yamashita, Benjamin D. Humphreys,
Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model
Wednesday, December 8th, 2021
ryn Dixon, Haojia Wu, Yoshiharu Muto, Parker Wilson and Benjamin Humphreys, “Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model”, JASN
Relaxin attenuates organ fibrosis via an angiotensin-type 2 receptor mechanism in aged hypertensive female rats
Tuesday, November 30th, 2021
Giannie Barsha, Sarah Walton, Edmund Kwok, Katrina Mirabito Colafella, Anita Pinar, Lucinda Hilliard Krause, Tracey Gaspari, Robert Widdop, Chrishan Samuel and Kate Denton, “Relaxin attenuates
Angiotensin II type 1 receptor agonistic autoantibody blockade improves postpartum hypertension and cardiac mitochondrial function in rat model of preeclampsia
Tuesday, November 16th, 2021
George W. Booz, Daniel Kennedy, Michael Bowling, Taprieka Robinson, Daniel Azubuike, Brandon Fisher, Karen Brooks, Pooja Chinthakuntla, Ngoc H. Hoang, Jonathan P. Hosler and Mark
Paraoxonase-3 Regulation of Cardiotonic Steroids Mediates Renal Injury and Dysfunction in a Dahl Salt Sensitive Model of Chronic Kidney Disease
Tuesday, November 16th, 2021
Chrysan J Mohammed, Sabitri Lamichhane, Prabhatchandra Dube, Sophia Soehnlen, Jacob Connolly, Andrew Kleinhenz, Dhilhani Faleel, Dragan Isailovic, Deepak Malhotra, Steven Haller, David J Kennedy, “Paraoxonase-3
Immune Cells as Drivers of Kidney Myofibroblast Formation and Fibrosis After Acute Cardiac Dysfunction”
Tuesday, November 16th, 2021
Kevin G. Burfeind, Yoshio Funahashi, Adam C. Munhall, Mahaba B. Eiwaz, Michael Hutchens, “Immune Cells as Drivers of Kidney Myofibroblast Formation and Fibrosis After Acute
Role of Megalin and Sex in AKI-CKD Transition due to Cardiorenal Syndrome Type 1
Tuesday, November 16th, 2021
Yoshio Funahashi, Jessica F. Hebert, Kevin G. Burfeind, Adam C. Munhall, Megan N. Nickerson, Tahnee Groat, Michael Hutchens, “Role of Megalin and Sex in AKI-CKD
UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation
Tuesday, November 16th, 2021
Sayaka Ogi, Hidetoshi Sunamoto, Hirohiko Fukiya, Futoshi Nara, Kazuhiro Onuma, “UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation”, Am.
Dexamethasone Attenuates Kidney Ischemia Reperfusion Injury in SD Rats by Mediating M1 Macrophage Cytokine Production
Tuesday, November 16th, 2021
Nataliya Skrypnyk, Henriette Frikke-Schmidt, David W. Frederick, Kamal Albarazanji, Gavin Lewis, Jianying Liu, Lili Guo, Qiu Li, Raul Camacho, Li-Jun Ma, Andrea R. Nawrocki, George
Hypertensive Diabetic Kidney Disease Increases the Severity of Experimental AKI
Tuesday, November 16th, 2021
Anna Menshikh, Rachel Delgado, Maya Brewer, Min Yang, Chris R. Kennedy, Haichun Yang, Mark P. de Caestecker, “Hypertensive Diabetic Kidney Disease Increases the Severity of
Glutathione S-Transferase and Clusterin, New Players in the Ischemic Preconditioning Renal Protection in a Murine Model of Ischemia and Reperfusion
Thursday, November 4th, 2021
Consuelo Pasten, Yeimi Herrera-Luna, Mauricio Lozano, Jocelyn Rocco, Cristobal Alvarado, Jéssica Liberona, Luis Michea, Carlos E Irarrázabal, “Glutathione S-Transferase and Clusterin, New Players in the
The non-steroidal mineralocorticoid receptor antagonist finerenone improves left ventricular function in preclinical chronic kidney disease
Monday, October 25th, 2021
Y Stephan, I Lima-Posada, M Souille, B Bonnard, R Palacios, L Nicol, P Kolkhof, F Jaisser, P Mulder, “The non-steroidal mineralocorticoid receptor antagonist finerenone improves
High salt diet-induced proximal tubular phenotypic changes and sodium-glucose cotransporter-2 expression are coordinated by cold shock Y-box binding protein-1
Friday, September 24th, 2021
Anja Bernhardt, Saskia Häberer, JingJing Xu, Hannah Damerau, Johannes Steffen, Charlotte Reichardt, Katharina Wolters, Hannes Steffen, Berend Isermann, Katrin Borucki, Nadine Artelt, Nicole Endlich, Renata
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Thursday, July 29th, 2021
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium Handling in Sprague Dawley Male Rats
Tuesday, May 25th, 2021
Irin Parvin, Madeline Gauthier, Melissa Dennis, Christopher Banek, “Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium
Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt Hypertensive Rats
Tuesday, May 25th, 2021
Madeline Gauthier, Melissa Rafet Dennis, Irin Parvin, Kyle Schwartz, Christopher Banek, “Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt
Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular Filtration Responses in Aging PT-Agtr1a-/- Mice
Tuesday, May 25th, 2021
Xiao Li, Rumana Hassan, Jia Zhuo, “Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular
Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction
Sunday, May 2nd, 2021
Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinweichi Nwosisi, Ming-Zhi Zhang, and Raymond C. Harris, “Activation
Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury
Tuesday, April 27th, 2021
Nirupama Ramkumar, Deborah Stuart, Caitlin S Peterson, Chunyan Hu, William Wheatley, Jae-Min Cho, J David Symons, and Donald E Kohan, “Loss of Soluble (Pro)renin Receptor
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition
Thursday, April 1st, 2021
Danielle E. Soranno, Lara Kirkbride-Romeo, Sara A. Wennersten, Kathy Ding, Maria A. Cavasin, Peter Baker, Christopher Altmann, Rushita A. Bagchi, Korey R. Haefner, Christian Steinkühler,
A dose-escalating toxicology study of the candidate biologic ELP-VEGF
Wednesday, March 24th, 2021
Jamarius P Waller, Stephen P Burke, Jason Engel, Alejandro R Chade, Gene L Bidwell 3rd, “A dose-escalating toxicology study of the candidate biologic ELP-VEGF”, Scientifc
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT- Agtr1a-/- Mice
Tuesday, March 9th, 2021
Xiao Chun Li, Ana Paula Oliveira Leite, Xiaowen Zheng, Chunling Zhao, Xu Chen, Liang Zhang, Xinchun Zhou, Isabelle Rubera, Michel Tauc, Jia Long Zhuo, “Proximal
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
Monday, January 25th, 2021
Stefan Rudloff, Mathilde Janot, Stephane Rodriguez1, Kevin Dessalle, Willi Jahnen-Dechent, & Uyen Huynh-Do, “Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress,”
No Evidence for Brain Renin-Angiotensin System Activation During DOCA-Salt Hypertension
Wednesday, January 13th, 2021
Estrellita Uij, Liwei Ren, Katrina M. Mirabito Colafella, Richard van Veghel1, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Jae B. Kim, Stephen Huang,
Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice
Thursday, October 29th, 2020
Sarah Faubel, “Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: PO0147 2020.
Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal Blood Pressure And Attenuates Angiotensin Ii-induced Hypertension By Increasing Glomerular Filtration And The Pressure-natriuresis Response
Monday, September 21st, 2020
Xiao C Li, Ana P Leite, Liang Zhang, Jia L Zhuo, “Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal
Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease
Monday, September 21st, 2020
Dominique M Bovee, Liwei Ren, Don Foster, A.H. J Danser, “Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease,” American Heart
Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy
Monday, September 21st, 2020
Satoshi Shimada, Allen W Cowley, “Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy,” American Heart Association Journals – Hypertension, September 9, 2020,
Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats with a prolonged high fat diet from an early age
Monday, July 13th, 2020
Lidia Oltra, Virginia Reverte, Antonio Tapia, Juan M. Moreno, Francisco J. Salazar, Maria T. Llinas, “Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats
Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity
Wednesday, June 24th, 2020
Bochra Tourki, Vasundhara Kain, Saame Raza Shaikh, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade, “Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and
Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After Unilateral Ischemic Injury
Wednesday, June 10th, 2020
Lies Moonen, Cristina Cuesta-Apausa, Francisco J. Lopez-Hernandez, Carlos Martinez Salgado, Patrick D’Haese, Benjamin Vervaet, “Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After
Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct
Wednesday, June 10th, 2020
Chongxu Shi, “Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct,” ERA-EDTA Meeting 2020, Nephrology Dialysis Transplantation 35 (Supplement 3):P0513.
Renomedullary Interstitial Cell Endothelin A Receptors Regulate BP and Renal Function
Monday, June 8th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Georgina Gyarmati, Chuan-Ming Hao, Peter Hansell and Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulate
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism
Wednesday, May 27th, 2020
Chongxu Shi, Tehyung Kim, Stefanie Steiger, Shrikant R. Mulay, Barbara M. Klinkhammer, Tobias Bäuerle, Maria Elena Melica4,5, Paola Romagnani, Diana Möckel, Maike Baues, Elmina Mammadova-Bach,
Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function
Wednesday, May 27th, 2020
Camila Kochi, Indira Pokkunuri, Ankita Salvi, Mohammad Asghar, Samina Salim, “Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function,” Journal Clinical and Experimental
Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function
Friday, April 24th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function,” Federation of
Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion Injury in Rats
Friday, April 24th, 2020
Zhengrong Guan, Wenguang Feng, Colton E. Remedies, Bailey A. McEachen, Paul W. Sanders, Edward W. Inscho, “Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion
Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction Independent of Cystogenesis
Wednesday, April 22nd, 2020
Jayalakshmi Lakshmipathi, Yang Gao, Chunyan Hu, Deborah Stuart, Jonathan Genzen, Nirupama Ramkumar and Donald E. Kohan, “Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction
Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia
Wednesday, April 8th, 2020
Shungang Zhang, MS; Joshua D. Breidenbach, MS; Fatimah K. Khalaf, MBCHB; Prabhatchandra R. Dube, PhD; Chrysan J. Mohammed, BA; Apurva Lad, MS; Stanislaw Stepkowski, PhD;
Targeted Inhibition of Gut Microbial TMAO Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
Wednesday, April 8th, 2020
Nilaksh Gupta, Jennifer A. Buffa, Adam B. Roberts, Naseer Sangwan, Sarah M. Skye, Lin Li, Karen J. Ho, John Varga, Joseph A. DiDonato, W.H. Wilson
α2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease
Wednesday, February 26th, 2020
Lydia Hering, Masudur Rahman, Henning Hoch, Lajos Markó, Guang Yang, Annika Reil, Mina Yakoub, Vikram Gupta, Sebastian A. Potthoff, Oliver Vonend, Donna L. Ralph, Susan
Murine models of renal ischaemia reperfusion injury: An opportunity for refinement using non-invasive monitoring methods
Friday, December 27th, 2019
Rachel Harwood, Joshua Bridge, Lorenzo Ressel, Lauren Scarfe, Jack Sharkey, Gabriella Czanner, Marta Garcia-Fiñana, Philip Kalra, Aghogho Odudu, Simon Kenny, Bettina Wilm, Patricia Murray, “Murine
Proximal Tubule-Specific Deletion of the NHE3 (Na+/H+ Exchanger 3) in the Kidney Attenuates Ang II (Angiotensin II)-Induced Hypertension in Mice
Thursday, December 19th, 2019
Xiao C. Li, Dongmin Zhu, Xu Chen, Xiaowen Zheng, Chunling Zhao, Jianfeng Zhang, Manoocher Soleimani, Isabelle Rubera, Michel Tauc, Xinchun Zhou, Jia L. Zhuo, “Proximal
Prenatal Sildenafil Therapy Improves Cardiovascular Function in Fetal Growth Restricted Offspring of Dahl Salt-Sensitive Rats
Tuesday, December 17th, 2019
Fieke Terstappen, Frank T. Spradley, Bhavisha A. Bakrania, Sinéad M. Clarke, Jaap A. Joles, Nina D. Paauw, Michael R. Garrett, A. Titia Lely, Jennifer M.
Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen
Sunday, December 8th, 2019
Estrellita Uij , Katrina M. Mirabito Colafella , Yuan Sun , Liwei Ren , Richard van Veghel , Ingrid M. Garrelds l, René de Vries
AT1-AA (Angiotensin II Type 1 Receptor Agonistic Autoantibody) Blockade Prevents Preeclamptic Symptoms in Placental Ischemic Rats
Wednesday, November 27th, 2019
Cunningham MW Jr, Castillo J, Ibrahim T, Cornelius DC, Campbell N, Amaral L, Vaka VR, Usry N, Williams JM, LaMarca B, “ AT1-AA (Angiotensin II
The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk
Thursday, November 21st, 2019
Eva-Maria Pastor-Arroyo, Nicole Gehring, Christiane Krudewig, Sarah Costantino, Carla Bettoni, Thomas Knöpfel, Sibylle Sabrautzki, Bettina Lorenz-Depiereux, Johanne Pastor, Tim M. Strom, Martin Hrabě de Angelis,
Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a Robust and Durable Antihypertensive Effect
Sunday, November 10th, 2019
Estrellita Uijl, Katrina M. Mirabito Colafella, Ewout J. Hoorn, Jae B. Kim, Donald J. Foster, Alexander H. Danser, “Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a
Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation
Wednesday, October 30th, 2019
Gregory J. Weber, Jaleyea Foster, Sathnur B. Pushpakumar, Utpal Sen, “Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized
Combined AT2 Receptor Stimulation AT1 Receptor Blockade Does Not Cause Renal Dysfunction
Monday, October 21st, 2019
Dhaniel Baraldi, Lucinda M Hilliard, Tracey A Gaspari, Kate M Denton, Robert E Widdop, “Combined AT2 Receptor Stimulation AT1 Receptor Blockade Does Not Cause Renal
Exposure to placental ischemia impairs postpartum maternal renal and cardiac function in rats
Thursday, October 17th, 2019
Nina D. Paauw, Jaap A Joles, Frank T. Spradley, Bhavisha Bakrania, Zsuzsanna K Zellenger, Arie Franx, Marianne C. Verhaar, Joey P. Granger, A. Titia Lely,
Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and Cardiopulmonary Resuscitation (CA/CPR) in Mice
Sunday, October 6th, 2019
Michael Hutchens, Rumie Wakasaki, Ian P. Coe,Mohammed Z. Ferdaus, James A. McCormick, Sharon Anderson, “Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and
Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats
Wednesday, September 25th, 2019
Hilliard LM, Colafella KM, Bulmer LL, Puelles VG, Singh RR, Ow CP, Gaspari T, Drummond GR, Evans RG, Vinh A, Denton KM, “Chronic recurrent dehydration