Chronic Kidney Disease (CKD)
CKD is a growing epidemic and has devastating consequences.

Therapy Dosing (CKD)
An assessment of GFR is used to determine if patients are eligible for receiving some therapies, such as guideline directed medical therapy for heart failure and anticancer drugs. Accurate assessment of kidney function can help reduce the risk of patients experiencing hyperkalemia from mineralocorticoid antagonists and toxicity from renally cleared chemotherapy.

Transplantation Donor Evaluation²
Evaluation of GFR is required as part of donor evaluation and is receiving increasing emphasis. Recent data from the general population demonstrate increased risks associated with reduced GFR. Data from kidney donors demonstrate increased risks of kidney disease after donation, including a small increase in the risk of kidney failure.

Kidney Function Assessment in the Hospital
Clinicians base patient categorization and sophisticated treatment decisions, sometimes extremely invasive and expensive therapies, on GFR levels. Bedside renal function assessments have the potential to yield information to aid in patient management. Identification of high-risk patients preoperatively could affect clinical decision making around surgical technique.